What is a common cause of inflammation in synovial fluid?

Rheumatoid arthritis is an autoimmune condition characterized by chronic inflammation of the joints, particularly affecting the synovial membrane, which lines the joints and produces synovial fluid. In rheumatoid arthritis, the immune system erroneously attacks the synovium, leading to inflammation that can result in pain, swelling, and potential joint damage. This inflammation is often reflected in the synovial fluid, which may show increased levels of inflammatory cells and proteins.

While other conditions can also impact synovial fluid, rheumatoid arthritis is specifically known for causing widespread inflammation that directly affects the synovial fluid composition and the health of the joints. In contrast, osteoporosis primarily involves a reduction in bone density without directly causing inflammation, a hernia does not typically involve the joints or synovial fluid, and although gout does cause inflammation, it does so through a different mechanism related to uric acid crystals rather than an autoimmune response targeting the synovial membrane.